Hypoxic Response Contributes to Altered Gene Expression and Precapillary Pulmonary Hypertension in Patients With Sickle Cell Disease | Zendy

Xu Zhang | Zendy; Wei Zhang | Zendy; ShwuFan Ma | Zendy; Ankit A. Desai | Zendy; Santosh L. Saraf | Zendy; Galina Miasniakova | Zendy; Adelina Sergueeva | Zendy; Tatiana Ammosova | Zendy; Min Xu | Zendy; Sergeï Nekhai | Zendy; Taimur Abbasi | Zendy; Nancy G. Casanova | Zendy; Martin H. Steinberg | Zendy; Clinton T. Baldwin | Zendy; Paola Sebastiani | Zendy; Josef T. Prchal | Zendy; Rick A. Kittles | Zendy; Joe G. N. Garcia | Zendy; Roberto F. Machado | Zendy; Victor R. Gordeuk | Zendy

Open Access

Hypoxic Response Contributes to Altered Gene Expression and Precapillary Pulmonary Hypertension in Patients With Sickle Cell Disease

Author(s) -

Xu Zhang,

Wei Zhang,

ShwuFan Ma,

Ankit A. Desai,

Santosh L. Saraf,

Galina Miasniakova,

Adelina Sergueeva,

Tatiana Ammosova,

Min Xu,

Sergeï Nekhai,

Taimur Abbasi,

Nancy G. Casanova,

Martin H. Steinberg,

Clinton T. Baldwin,

Paola Sebastiani,

Josef T. Prchal,

Rick A. Kittles,

Joe G. N. Garcia,

Roberto F. Machado,

Victor R. Gordeuk

Publication year - 2014

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.005296

Subject(s) - medicine , pulmonary hypertension , sickle cell anemia , odds ratio , hypoxia (environmental) , acute chest syndrome , gastroenterology , cardiology , immunology , endocrinology , pathology , disease , chemistry , organic chemistry , oxygen

We postulated that the hypoxic response in sickle cell disease (SCD) contributes to altered gene expression and pulmonary hypertension, a complication associated with early mortality.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research