Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase | Zendy

Catharina Belge | Zendy; Joanna Hammond | Zendy; Emilie DuboisDeruy | Zendy; Boris Manoury | Zendy; Julien Hamelet | Zendy; Christophe Beauloye | Zendy; Andreas Markl | Zendy; AnneCatherine Pouleur | Zendy; Luc Bertrand | Zendy; Hrag Esfahani | Zendy; Karima Jnaoui | Zendy; Konrad R. Götz | Zendy; Viacheslav O. Nikolaev | Zendy; Annelies Vanderper | Zendy; Paul Herijgers | Zendy; Irina Lobysheva | Zendy; Guido Iaccarino | Zendy; Denise HilfikerKleiner | Zendy; Geneviève Tavernier | Zendy; Dominique Langin | Zendy; Chantal Dessy | Zendy; JeanLuc Balligand | Zendy

Open Access

Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase

Author(s) -

Catharina Belge,

Joanna Hammond,

Emilie DuboisDeruy,

Boris Manoury,

Julien Hamelet,

Christophe Beauloye,

Andreas Markl,

AnneCatherine Pouleur,

Luc Bertrand,

Hrag Esfahani,

Karima Jnaoui,

Konrad R. Götz,

Viacheslav O. Nikolaev,

Annelies Vanderper,

Paul Herijgers,

Irina Lobysheva,

Guido Iaccarino,

Denise HilfikerKleiner,

Geneviève Tavernier,

Dominique Langin,

Chantal Dessy,

JeanLuc Balligand

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.004940

Subject(s) - medicine , phenylephrine , endocrinology , nitric oxide synthase , muscle hypertrophy , myocyte , angiotensin ii , endothelial nos , nitric oxide , fibrosis , receptor , enos , blood pressure

β1-2-adrenergic receptors (AR) are key regulators of cardiac contractility and remodeling in response to catecholamines. β3-AR expression is enhanced in diseased human myocardium, but its impact on remodeling is unknown.

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