Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia | Zendy

Lucy C. Chappell | Zendy; Suzy Duckworth | Zendy; Paul T. Seed | Zendy; Melanie Griffin | Zendy; Jenny Myers | Zendy; Lucy Mackillop | Zendy; Nigel Simpson | Zendy; Jason Waugh | Zendy; Dilly Anumba | Zendy; Louise C. Kenny | Zendy; Christopher W.G. Redman | Zendy; Andrew Shennan | Zendy

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Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia

Author(s) -

Lucy C. Chappell,

Suzy Duckworth,

Paul T. Seed,

Melanie Griffin,

Jenny Myers,

Lucy Mackillop,

Nigel Simpson,

Jason Waugh,

Dilly Anumba,

Louise C. Kenny,

Christopher W.G. Redman,

Andrew Shennan

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.003215

Subject(s) - preeclampsia , medicine , gestation , placental growth factor , obstetrics , pregnancy , proteinuria , prospective cohort study , receiver operating characteristic , genetics , biology , kidney

Hypertensive disorders of pregnancy are a major contributor to death and disability for pregnant women and their infants. The diagnosis of preeclampsia by using blood pressure and proteinuria is of limited use because they are tertiary, downstream features of the disease. Placental growth factor (PlGF) is an angiogenic factor, a secondary marker of associated placental dysfunction in preeclampsia, with known low plasma concentrations in the disease.

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