Predicting the Risk of Venous Thromboembolism in Patients Hospitalized With Heart Failure
Author(s) -
Alexandre Mebazaa,
Theodore E. Spiro,
Harry R. Büller,
Lloyd Haskell,
Dayi Hu,
Russell D. Hull,
Geno J. Merli,
Sebastian Schellong,
Alex C. Spyropoulos,
Victor F. Tapson,
Yoriko De Sanctis,
Alexander T. Cohen
Publication year - 2014
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.113.003126
Subject(s) - medicine , venous thromboembolism , heart failure , intensive care medicine , cardiology , thrombosis
Whether heart failure (HF) increases the risk of venous thromboembolism (VTE) is not well established. In the phase III MAGELLAN (Multicenter, rAndomized, parallel Group Efficacy and safety study for the prevention of venous thromboembolism in hospitalized medically iLL patients comparing rivaroxabAN with enoxaparin) trial, extended-duration rivaroxaban was compared with standard-duration enoxaparin followed by placebo for VTE prevention in 8101 hospitalized acutely ill patients with or without HF. The aim of this analysis was to evaluate the relationship between HF severity and the risk of VTE in MAGELLAN patients.
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