Open AccessImpaired Cholesterol Metabolism and Enhanced Atherosclerosis in Clock Mutant Mice
Author(s) -
Xiaoyue Pan,
XianCheng Jiang,
M. Mahmood Hussain
Publication year - 2013
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.113.002885
Subject(s) - chylomicron , medicine , endocrinology , cholesterol , apolipoprotein e , apolipoprotein b , sterol o acyltransferase , circadian clock , reverse cholesterol transport , lipoprotein , microsomal triglyceride transfer protein , biology , very low density lipoprotein , circadian rhythm , disease
Clock is a key transcription factor that positively controls circadian regulation. However, its role in plasma cholesterol homeostasis and atherosclerosis has not been studied.
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