Role of Extracellular RNA in Atherosclerotic Plaque Formation in Mice | Zendy

Sakine Simsekyilmaz | Zendy; Héctor A. Cabrera-Fuentes | Zendy; Svenja Meiler | Zendy; Sawa Kostin | Zendy; Yvonne Baumer | Zendy; Elisa A. Liehn | Zendy; Christian Weber | Zendy; William A. Boisvert | Zendy; Klaus T. Preissner | Zendy; Alma Zernecke | Zendy

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Role of Extracellular RNA in Atherosclerotic Plaque Formation in Mice

Author(s) -

Sakine Simsekyilmaz,

Héctor A. Cabrera-Fuentes,

Svenja Meiler,

Sawa Kostin,

Yvonne Baumer,

Elisa A. Liehn,

Christian Weber,

William A. Boisvert,

Klaus T. Preissner,

Alma Zernecke

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.002562

Subject(s) - neointima , proinflammatory cytokine , medicine , inflammation , endocrinology , apolipoprotein e , tumor necrosis factor alpha , monocyte , apolipoprotein b , cholesterol , restenosis , disease , stent

Atherosclerosis and vascular remodeling after injury are driven by inflammation and mononuclear cell infiltration. Extracellular RNA (eRNA) has recently been implicated to become enriched at sites of tissue damage and to act as a proinflammatory mediator. Here, we addressed the role of eRNA in high-fat diet-induced atherosclerosis and neointima formation after injury in atherosclerosis-prone mice.

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