Vascular Injury Involves the Overoxidation of Peroxiredoxin Type II and Is Recovered by the Peroxiredoxin Activity Mimetic That Induces Reendothelialization | Zendy

Dong Hoon Kang | Zendy; Doo Jae Lee | Zendy; Jiran Kim | Zendy; Joo Young Lee | Zendy; Hyunwoo Kim | Zendy; Kihwan Kwon | Zendy; W. Robert Taylor | Zendy; Hanjoong Jo | Zendy; Sang Won Kang | Zendy

Open Access

Vascular Injury Involves the Overoxidation of Peroxiredoxin Type II and Is Recovered by the Peroxiredoxin Activity Mimetic That Induces Reendothelialization

Author(s) -

Dong Hoon Kang,

Doo Jae Lee,

Jiran Kim,

Joo Young Lee,

Hyunwoo Kim,

Kihwan Kwon,

W. Robert Taylor,

Hanjoong Jo,

Sang Won Kang

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.001725

Subject(s) - neointimal hyperplasia , vascular smooth muscle , medicine , intimal hyperplasia , peroxiredoxin , oxidative stress , hyperplasia , intracellular , pathology , microbiology and biotechnology , peroxidase , biochemistry , chemistry , biology , enzyme , smooth muscle , restenosis , stent

Typical 2-Cys peroxiredoxin (Prx) is inactivated by overoxidation of the peroxidatic cysteine residue under oxidative stress. However, the significance in the context of vascular disease is unknown.

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