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We thank Llau et al for their comments on our editorial.1 The challenge in periprocedural management of anticoagulated patients focuses on the need to balance the risk of thromboembolism (in case of anticoagulation interruption) with the risk of bleeding during the procedure (in case of anticoagulation continuation). Some procedures have demonstrated improved outcomes when oral anticoagulation was not discontinued (eg, minor dental, dermatologic procedures, or cataract surgery), and the meta-analysis performed by Siegal et al2 showed an increased risk of bleeding with similar thrombotic risk among patients who underwent periprocedural bridging therapy. Similar …

Response to Letter Regarding Article, “Bridging Evidence-Based Practice and Practice-Based Evidence in Periprocedural Anticoagulation”