Thrombolytic Therapy for the Treatment of Prosthetic Heart Valve Thrombosis in Pregnancy With Low-Dose, Slow Infusion of Tissue-Type Plasminogen Activator | Zendy

Mehmet Özkan | Zendy; Beytullah Çakal | Zendy; Süleyman Karakoyun | Zendy; Ozan Mustafa Gürsoy | Zendy; Cihan Çevik | Zendy; Macit Kalçık | Zendy; Ali Emrah Oğuz | Zendy; Sabahattin Gündüz | Zendy; Mehmet Ali Astarcıoğlu | Zendy; Ahmet Çağrı Aykan | Zendy; Zübeyde Bayram | Zendy; Murat Biteker | Zendy; Evren Kaynak | Zendy; Gökhan Kahveci | Zendy; Nilüfer Ekşi Duran | Zendy; Mustafa Yıldız | Zendy

Open Access

Thrombolytic Therapy for the Treatment of Prosthetic Heart Valve Thrombosis in Pregnancy With Low-Dose, Slow Infusion of Tissue-Type Plasminogen Activator

Author(s) -

Mehmet Özkan,

Beytullah Çakal,

Süleyman Karakoyun,

Ozan Mustafa Gürsoy,

Cihan Çevik,

Macit Kalçık,

Ali Emrah Oğuz,

Sabahattin Gündüz,

Mehmet Ali Astarcıoğlu,

Ahmet Çağrı Aykan,

Zübeyde Bayram,

Murat Biteker,

Evren Kaynak,

Gökhan Kahveci,

Nilüfer Ekşi Duran,

Mustafa Yıldız

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.113.001145

Subject(s) - medicine , thrombosis , surgery , pregnancy , plasminogen activator , thrombus , tissue plasminogen activator , t plasminogen activator , complication , cardiology , vascular disease , genetics , biology

Prosthetic valve thrombosis during pregnancy is life-threatening for mother and fetus, and the treatment of this complication is unclear. Cardiac surgery in pregnancy is associated with very high maternal and fetal mortality and morbidity. Thrombolytic therapy has rarely been used in these patients. The aim of this study is to evaluate the safety and efficacy of low-dose (25 mg), slow infusion (6 hours) of tissue-type plasminogen activator for the treatment of prosthetic valve thrombosis in pregnant women.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research