Response to Letter Regarding Article, “Prediction of Progression of Coronary Artery Disease and Clinical Outcomes Using Vascular Profiling of Endothelial Shear Stress and Arterial Plaque Characteristics: The PREDICTION Study” | Zendy

Peter H. Stone | Zendy; Shigeru Saito | Zendy; Saeko Takahashi | Zendy; Yasuhiro Makita | Zendy; Shigeru Nakamura | Zendy; Tomohiro Kawasaki | Zendy; Akihiko Takahashi | Zendy; Takaaki Katsuki | Zendy; Sunao Nakamura | Zendy; Atsuo Namiki | Zendy; Atsushi Hirohata | Zendy; Toshiyuki Matsumura | Zendy; Seiji Yamazaki | Zendy; Hiroyoshi Yokoi | Zendy; Shinji Tanaka | Zendy; Satoru Otsuji | Zendy; Fuminobu Yoshimachi | Zendy; Junko Honye | Zendy; Dawn Harwood | Zendy; Martha Reitman | Zendy; Ahmet U. Coskun | Zendy; Michail I. Papafaklis | Zendy; Charles L. Feldman | Zendy

Open Access

Response to Letter Regarding Article, “Prediction of Progression of Coronary Artery Disease and Clinical Outcomes Using Vascular Profiling of Endothelial Shear Stress and Arterial Plaque Characteristics: The PREDICTION Study”

Author(s) -

Peter H. Stone,

Shigeru Saito,

Saeko Takahashi,

Yasuhiro Makita,

Shigeru Nakamura,

Tomohiro Kawasaki,

Akihiko Takahashi,

Takaaki Katsuki,

Sunao Nakamura,

Atsuo Namiki,

Atsushi Hirohata,

Toshiyuki Matsumura,

Seiji Yamazaki,

Hiroyoshi Yokoi,

Shinji Tanaka,

Satoru Otsuji,

Fuminobu Yoshimachi,

Junko Honye,

Dawn Harwood,

Martha Reitman,

Ahmet U. Coskun,

Michail I. Papafaklis,

Charles L. Feldman

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.147561

Subject(s) - medicine , cardiology , coronary artery disease , profiling (computer programming) , vascular disease , artery , computer science , operating system

We agree entirely with Dr Kaneda that both the local endothelial shear stress (ESS) stimulus and the local atherosclerotic plaque change may occur in a highly focal manner within each 3-mm segment, and one must look at both ESS and the arterial wall in portions of the wall circumference to assess plaque behavior accurately. In our original article,1 we were limited by space to describe the effect of focal ESS on focal plaque progression around the circumference of the 3-mm segment, but we presented those results from a database study at the American Heart Association Scientific Sessions in 2012.2 Focal eccentric plaque growth in a portion of the circumference of the arterial wall is indeed strongly related …

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