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Response to Letter Regarding Article, “Sustained Ventricular Tachycardia and Ventricular Fibrillation Complicating Non–ST-Segment Elevation Acute Coronary Syndromes”
Author(s) -
Jonathan P. Piccini,
Jennifer A. White,
Rajendra H. Mehta,
Yuliya Lokhnygina,
Sana M. AlKhatib,
Pierluigi Tricoci,
Robert M. Califf,
Robert A. Harrington,
L. Kristin Newby,
Charles V. Pollack,
Gilles Montalescot,
Frans Van de Werf,
C. Michael Gibson,
Robert P. Giugliano
Publication year - 2013
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.112.147546
Subject(s) - medicine , ventricular fibrillation , cardiology , ventricular tachycardia , st segment , st elevation , electrocardiography , myocardial infarction
We appreciate the comments and suggestions made by Bouguin et al. As they point out, there are several important limitations of our analysis, including the lack of cause-specific mortality in long-term follow-up.1 Although the Early Glycoprotein IIb/IIIa Inhibition in NSTE ACS (EARLY ACS) trial captured cause of death at 30 days, these data were unavailable at 1 year. However, our suggested recommendations are well supported by the data. A key finding in our analysis was that ventricular tachycardia/ventricular fibrillation is just as likely to occur ≥48 hours after a non–ST-segment elevation acute coronary syndrome as within the immediate post–acute coronary syndrome period (0–48 hours). Thus, aggressive in-hospital monitoring through discharge seems warranted. We agree with Bouguin et al that management of arrhythmic risk after discharge in patients who develop …

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