Response to Letter Regarding Article, “Short- and Long-Term Outcomes With Drug-Eluting and Bare-Metal Coronary Stents: A Mixed-Treatment Comparison Analysis of 117 762 Patient-years of Follow-up From Randomized Trials”

Sharma and Chatterjee compare and contrast our publication1 with a recent publication on stent thrombosis2 and are concerned with “divergent” results of the 2 studies. A thorough reading of both the articles shows that the results of the 2 articles are concordant, demonstrating that everolimus-eluting stents reduce the risk of stent thrombosis compared with other drug-eluting stents and even bare-metal stents. The differences are due largely to the design of the 2 studies. First, the focus of the Palmerini et al2 article was on stent thrombosis, whereas our focus was on not only stent thrombosis, but also other efficacy and safety outcomes, as outlined below. Second, Palmerini et al excluded studies that did not report stent …