Pulmonary Artery Hypertension Associated With Systemic Scleroderma

A 68-year–old woman had been experiencing Raynaud symptom, palpitation of the heart, and short breath in walking stairs or slopes for 7 years. Recently, these symptoms had rapidly become worse. She admitted to our hospital. At that time, she was diagnosed with systemic scleroderma (limited scleroderma). Pulmonary hypertension was pointed out by echocardiography (estimated pulmonary artery pressure 35–43 mmHg), and she was suspected as having pulmonary artery hypertension associated with systemic scleroderma.At the admission, laboratory data showed as follows: plasma d-dimer 0.2 μg/mL, IgM 419.3 mg/dL, antinuclear antibody ×640, …