Cytochrome P450 Subfamily 2J Polypeptide 2 Expression and Circulating Epoxyeicosatrienoic Metabolites in Preeclampsia | Zendy

Florian Herse | Zendy; Babbette LaMarca | Zendy; Carl A. Hubel | Zendy; Tea Kaartokallio | Zendy; A. Inkeri Lokki | Zendy; Eeva Ekholm | Zendy; Hannele Laivuori | Zendy; Martin Gauster | Zendy; Berthold Huppertz | Zendy; Meryam Sugulle | Zendy; Michael J. Ryan | Zendy; Sarah Novotny | Zendy; Justin Brewer | Zendy; Joon-Keun Park | Zendy; Michael Kacik | Zendy; Joachim Hoyer | Zendy; Stefan Verlohren | Zendy; Gerd Wallukat | Zendy; Michael Rothe | Zendy; Friedrich C. Luft | Zendy; Dominik N. Müller | Zendy; WolfHagen Schunck | Zendy; Anne Cathrine Staff | Zendy; Ralf Dechend | Zendy

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Cytochrome P450 Subfamily 2J Polypeptide 2 Expression and Circulating Epoxyeicosatrienoic Metabolites in Preeclampsia

Author(s) -

Florian Herse,

Babbette LaMarca,

Carl A. Hubel,

Tea Kaartokallio,

A. Inkeri Lokki,

Eeva Ekholm,

Hannele Laivuori,

Martin Gauster,

Berthold Huppertz,

Meryam Sugulle,

Michael J. Ryan,

Sarah Novotny,

Justin Brewer,

Joon-Keun Park,

Michael Kacik,

Joachim Hoyer,

Stefan Verlohren,

Gerd Wallukat,

Michael Rothe,

Friedrich C. Luft,

Dominik N. Müller,

WolfHagen Schunck,

Anne Cathrine Staff,

Ralf Dechend

Publication year - 2012

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.127340

Subject(s) - endocrinology , preeclampsia , medicine , placenta , epoxygenase , decidua , epoxyeicosatrienoic acid , cytochrome p450 , biology , fetus , pregnancy , genetics , metabolism

Preeclampsia is a multisystem disorder of pregnancy, originating in the placenta. Cytochrome P450 (CYP)-dependent eicosanoids regulate vascular function, inflammation, and angiogenesis, which are mechanistically important in preeclampsia.

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