Reduction in First and Recurrent Cardiovascular Events With Ticagrelor Compared With Clopidogrel in the PLATO Study
Author(s) -
Payal Kohli,
Lars Wallentin,
Eric Reyes,
Jay Horrow,
Steen Husted,
Dominick J. Angiolillo,
Diego Ardissino,
Gerald Maurer,
João Morais,
José Carlos Nicolau,
Ali Oto,
Robert F. Storey,
Stefan James,
Christopher P. Can
Publication year - 2013
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.112.124248
Subject(s) - ticagrelor , medicine , hazard ratio , cardiology , myocardial infarction , clopidogrel , acute coronary syndrome , stroke (engine) , proportional hazards model , confidence interval , mechanical engineering , engineering
We sought to evaluate the effect of potent platelet inhibition after acute coronary syndrome on total (ie, first and recurrent) occurrences of any of the primary outcome events (e.g., cardiovascular death, myocardial infarction, and stroke) as well as on other ischemic events, such as urgent revascularization, (severe) recurrent ischemia, transient ischemic attacks, and arterial thrombotic events.
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