Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/Proteoglycan Interactions | Zendy

Patricia Rueda | Zendy; Adèle Richart | Zendy; Alice Récalde | Zendy; Paméla Gasse | Zendy; José Vilar | Zendy; Coralie L. Guérin | Zendy; Hugues LortatJacob | Zendy; Paulo Vieira | Zendy; Frano̧ise Baleux | Zendy; Fabrice Chrétien | Zendy; Fernando ArenzanaSeisdedos | Zendy; JeanSébastien Silvestre | Zendy

Open Access

Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/Proteoglycan Interactions

Author(s) -

Patricia Rueda,

Adèle Richart,

Alice Récalde,

Paméla Gasse,

José Vilar,

Coralie L. Guérin,

Hugues LortatJacob,

Paulo Vieira,

Frano̧ise Baleux,

Fabrice Chrétien,

Fernando ArenzanaSeisdedos,

JeanSébastien Silvestre

Publication year - 2012

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.113290

Subject(s) - medicine , proteoglycan , microbiology and biotechnology , homeostasis , neuroscience , anatomy , biology , cartilage

Interaction with heparan sulfate proteoglycans is supposed to provide chemokines with the capacity to immobilize on cell surface and extracellular matrix for accomplishing both tissue homing and signaling of attracted cells. However, the consequences of the exclusive invalidation of such interaction on the roles played by endogenous chemokines in vivo remain unascertained.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research