Prospective Study of Restless Legs Syndrome and Coronary Heart Disease Among Women
Author(s) -
Yanping Li,
Arthur S. Walters,
Stephanie E. Chiuve,
Eric B. Rimm,
John W. Winkelman,
Xiang Gao
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.112.112698
Subject(s) - medicine , hazard ratio , confidence interval , prospective cohort study , myocardial infarction , relative risk , stroke (engine) , restless legs syndrome , cardiology , psychiatry , mechanical engineering , neurology , engineering
Previous cross-sectional studies suggested a positive association between restless legs syndrome (RLS) and coronary heart disease (CHD). This observation was not confirmed by subsequent prospective studies. However, these prospective studies did not take into account the duration of RLS symptoms. Therefore, we prospectively examined whether RLS was associated with an increased risk of CHD in women who participated in the Nurses' Health Study, taking into account the duration of RLS symptoms.
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