Open AccessImmediate Antioxidant and Antiplatelet Effect of Atorvastatin via Inhibition of Nox2
Author(s) -
Pasquale Pignatelli,
Roberto Carnevale,
Daniele Pastori,
Roberto Cangemi,
Laura Napoleone,
Simona Bartimoccia,
Cristiocella,
Stefania Basili,
Francesco Violi
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.112.095554
Subject(s) - medicine , platelet activation , atorvastatin , endocrinology , nitric oxide , platelet , thromboxane , isoprostanes , pharmacology , isoprostane , oxidative stress , lipid peroxidation
Statins exert an antithrombotic effect in patients at risk of or with acute thrombosis, but no study has investigated whether this effect is immediate and whether there is an underline mechanism.
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