Letter by Gómez et al Regarding Article, “Colchicine Reduces Postoperative Atrial Fibrillation: Results of the Colchicine for the Prevention of the Postpericardiotomy Syndrome (COPPS) Atrial Fibrillation Substudy”
Author(s) -
Mabel Fernanda Gómez Mejia,
Andrés Felipe Buitrago Sandoval,
Jesús Hernando Díaz Acevedo
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.112.094078
Subject(s) - medicine , atrial fibrillation , cardiology , colchicine , surgery
We appreciate your interest in the COPPS postoperative atrial fibrillation (POAF) substudy.1 Your letter has 2 main queries: The time of colchicine administration, and the possible beneficial effects of concomitant use of β-blockers as a potential confounding factor in the trial results.The COPPS-POAF substudy is the first trial to test the hypothesis that colchicine may be useful and safe for POAF prevention based on preliminary findings regarding prevention of postpericardiotomy syndrome by Finkelstein et al2 and evidence that anti-inflammatory therapy, such as corticosteroids, …
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