High-Dose Statin Therapy in Patients With Stable Coronary Artery Disease | Zendy

Johannes A N Dorresteijn | Zendy; S. Matthijs Boekholdt | Zendy; Yolanda van der Graaf | Zendy; John J.P. Kastelein | Zendy; John C. LaRosa | Zendy; Terje R. Pedersen | Zendy; David A. DeMicco | Zendy; Paul M. Ridker | Zendy; Nancy R. Cook | Zendy; Frank L.J. Visseren | Zendy

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High-Dose Statin Therapy in Patients With Stable Coronary Artery Disease

Author(s) -

Johannes A N Dorresteijn,

S. Matthijs Boekholdt,

Yolanda van der Graaf,

John J.P. Kastelein,

John C. LaRosa,

Terje R. Pedersen,

David A. DeMicco,

Paul M. Ridker,

Nancy R. Cook,

Frank L.J. Visseren

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.000712

Subject(s) - medicine , myocardial infarction , cardiology , coronary artery disease , atorvastatin , statin , heart failure , hazard ratio , diabetes mellitus , confidence interval , endocrinology

Clinicians need to identify coronary artery disease patients for whom the benefits of high-dose versus usual-dose statin therapy outweigh potential harm. We therefore aimed to develop and validate a model for prediction of the incremental treatment effect of high-dose statins for individual patients in terms of reduction of 5-year absolute risk for myocardial infarction, stroke, coronary death, or cardiac resuscitation.

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