Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk | Zendy

Marylyn D. Ritchie | Zendy; Joshua C. Denny | Zendy; Rebecca L. Zuvich | Zendy; Dana C. Crawford | Zendy; Jonathan S. Schildcrout | Zendy; Lisa Bastarache | Zendy; Andrea H. Ramirez | Zendy; Jonathan D. Mosley | Zendy; Jill M. Pulley | Zendy; Melissa Basford | Zendy; Yuki Bradford | Zendy; Luke V. Rasmussen | Zendy; Jyotishman Pathak | Zendy; Christopher G. Chute | Zendy; Iftikhar J. Kullo | Zendy; Catherine A. McCarty | Zendy; Rex L. Chisholm | Zendy; Abel Kho | Zendy; Christopher S. Carlson | Zendy; Eric B. Larson | Zendy; Gail P. Jarvik | Zendy; a Sotoodehnia | Zendy; Teri A. Manolio | Zendy; Rongling Li | Zendy; Daniel R. Masys | Zendy; Jonathan L. Haines | Zendy; Dan M. Roden | Zendy

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Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk

Author(s) -

Marylyn D. Ritchie,

Joshua C. Denny,

Rebecca L. Zuvich,

Dana C. Crawford,

Jonathan S. Schildcrout,

Lisa Bastarache,

Andrea H. Ramirez,

Jonathan D. Mosley,

Jill M. Pulley,

Melissa Basford,

Yuki Bradford,

Luke V. Rasmussen,

Jyotishman Pathak,

Christopher G. Chute,

Iftikhar J. Kullo,

Catherine A. McCarty,

Rex L. Chisholm,

Abel Kho,

Christopher S. Carlson,

Eric B. Larson,

Gail P. Jarvik,

a Sotoodehnia,

Teri A. Manolio,

Rongling Li,

Daniel R. Masys,

Jonathan L. Haines,

Dan M. Roden

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.000604

Subject(s) - phenome , medicine , cardiac arrhythmia , genome , electrical conduction system of the heart , cardiology , computational biology , genetics , electrocardiography , atrial fibrillation , gene , biology

ECG QRS duration, a measure of cardiac intraventricular conduction, varies ≈2-fold in individuals without cardiac disease. Slow conduction may promote re-entrant arrhythmias.

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