Association Between Postresuscitation Partial Pressure of Arterial Carbon Dioxide and Neurological Outcome in Patients With Post–Cardiac Arrest Syndrome | Zendy

Brian W. Roberts | Zendy; J. Hope Kilgan | Zendy; Michael E. Chansky | Zendy; Neil Mittal | Zendy; Jonathan Wooden | Zendy; Stephen Trzeciak | Zendy

Open Access

Association Between Postresuscitation Partial Pressure of Arterial Carbon Dioxide and Neurological Outcome in Patients With Post–Cardiac Arrest Syndrome

Author(s) -

Brian W. Roberts,

J. Hope Kilgan,

Michael E. Chansky,

Neil Mittal,

Jonathan Wooden,

Stephen Trzeciak

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.000168

Subject(s) - hypocapnia , medicine , hypercapnia , return of spontaneous circulation , anesthesia , confidence interval , odds ratio , cerebral blood flow , cardiology , arterial blood , resuscitation , cardiopulmonary resuscitation , acidosis

Partial pressure of arterial CO2 (Paco(2)) is a regulator of cerebral blood flow after brain injury. Recent guidelines for the management of cardiac arrest recommend maintaining Paco(2) at 40 to 45 mm Hg after successful resuscitation; however, there is a paucity of data on the prevalence of Paco(2) derangements during the post-cardiac arrest period and its association with outcome.

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