Mechanically Unloading the Left Ventricle Before Coronary Reperfusion Reduces Left Ventricular Wall Stress and Myocardial Infarct Size | Zendy

Navin K. Kapur | Zendy; Vikram Paruchuri | Zendy; Jose Angel Urbano-Morales | Zendy; Emily Mackey | Zendy; Gerard H. Daly | Zendy; Xiaoying Qiao | Zendy; Natesa G. Pandian | Zendy; George Perides | Zendy; Richard H. Karas | Zendy

Open Access

Mechanically Unloading the Left Ventricle Before Coronary Reperfusion Reduces Left Ventricular Wall Stress and Myocardial Infarct Size

Author(s) -

Navin K. Kapur,

Vikram Paruchuri,

Jose Angel Urbano-Morales,

Emily Mackey,

Gerard H. Daly,

Xiaoying Qiao,

Natesa G. Pandian,

George Perides,

Richard H. Karas

Publication year - 2013

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.112.000029

Subject(s) - medicine , cardiology , ventricle , myocardial infarction , reperfusion injury , artery , ischemia , occlusion , reperfusion therapy , infarction

Ischemia/reperfusion injury worsens infarct size, a major determinant of morbidity and mortality after acute myocardial infarction (MI). We tested the hypothesis that reducing left ventricular wall stress with a percutaneous left atrial-to-femoral artery centrifugal bypass system while delaying coronary reperfusion limits myocardial injury in a model of acute MI.

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