A Strong Regenerative Ability of Cardiac Stem Cells Derived From Neonatal Hearts | Zendy

David Simpson | Zendy; Rachana Mishra | Zendy; Sudhish Sharma | Zendy; Saik Kia Goh | Zendy; Savitha Deshmukh | Zendy; Sunjay Kaushal | Zendy

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A Strong Regenerative Ability of Cardiac Stem Cells Derived From Neonatal Hearts

Author(s) -

David Simpson,

Rachana Mishra,

Sudhish Sharma,

Saik Kia Goh,

Savitha Deshmukh,

Sunjay Kaushal

Publication year - 2012

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.111.084699

Subject(s) - medicine , stem cell , regeneration (biology) , progenitor cell , cardiac function curve , regenerative medicine , adult stem cell , flow cytometry , andrology , pathology , immunology , microbiology and biotechnology , cardiology , endothelial stem cell , biology , in vitro , heart failure , biochemistry

Human cardiac stem cells (CSCs) promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of CSCs in very young patients with nonischemic congenital heart defects has not been explored. We hypothesized that isolated neonatal-derived CSCs may have a higher regenerative ability than adult-derived CSCs and might address the structural deficiencies of congenital heart disease.

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