Evidence of a Vicious Cycle in Mitral Regurgitation With Prolapse | Zendy

Kyoko Otani | Zendy; Masaaki Takeuchi | Zendy; Kyoko Kaku | Zendy; Nobuhiko Haruki | Zendy; Hidetoshi Yoshitani | Zendy; Masataka Eto | Zendy; Masahito Tamura | Zendy; Masahiro Okazaki | Zendy; Haruhiko Abe | Zendy; Yoshihisa Fujino | Zendy; Yousuke Nishimura | Zendy; Robert A. Levine | Zendy; Yutaka Otsuji | Zendy

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Evidence of a Vicious Cycle in Mitral Regurgitation With Prolapse

Author(s) -

Kyoko Otani,

Masaaki Takeuchi,

Kyoko Kaku,

Nobuhiko Haruki,

Hidetoshi Yoshitani,

Masataka Eto,

Masahito Tamura,

Masahiro Okazaki,

Haruhiko Abe,

Yoshihisa Fujino,

Yousuke Nishimura,

Robert A. Levine,

Yutaka Otsuji

Publication year - 2012

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.111.084178

Subject(s) - medicine , mitral regurgitation , mitral valve prolapse , cardiology , regurgitation (circulation) , mitral valve

In patients with mitral valve prolapse, nonprolapsed leaflets are often apically tented. We hypothesized that secondary left ventricular dilatation attributed to primary mitral regurgitation (MR) causes papillary muscle (PM) displacement, resulting in this leaflet tenting/tethering, and that secondary tethering further exacerbates malcoaptation and contributes to MR severity.

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