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Right or Left Ventricular Pacing in Young Minipigs With Chronic Atrioventricular Block
Author(s) -
Aida Salameh,
Stefan Dhein,
Katja Blanke,
Ardawan Rastan,
Bahi Hiyasat,
Anna Dietze,
Axel Sobiraij,
Ingo Dähnert,
Jan Janoušek
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.079087
Subject(s) - medicine , atrioventricular block , cardiology , heart block , ventricular pacing , anesthesia , electrocardiography , heart failure
Left ventricular (LV) dyssynchrony may occur as a result of right ventricular (RV) pacing and is a known risk factor for the development of heart failure. In children with complete atrioventricular block, pacing-induced dyssynchrony lasting for decades might be especially deleterious for LV function. To determine the hemodynamic and ultrastructural remodeling after either RV free wall or LV apical pacing, we used a chronic minipig model.

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