Epoxyeicosatrienoic Acids Contribute With Altered Nitric Oxide and Endothelin-1 Pathways to Conduit Artery Endothelial Dysfunction in Essential Hypertension
Author(s) -
Jérémy Bellien,
Michèle Iacob,
Isabelle RémyJouet,
Danièle Lucas,
Christelle Monteil,
Laurence Gutierrez,
Cathy Vendeville,
Yvonne Dréano,
Alain Mercier,
Christian Thuillez,
Robinson Joannidès
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.070680
Subject(s) - medicine , fluconazole , nitric oxide , endothelial dysfunction , essential hypertension , endothelin 1 , reactive hyperemia , reactive oxygen species , vasodilation , endothelium , brachial artery , endocrinology , omega n methylarginine , endothelin receptor , cardiology , pharmacology , nitric oxide synthase , blood pressure , biochemistry , chemistry , antifungal , receptor , dermatology
We sought to clarify, using functional and biological approaches, the role of epoxyeicosatrienoic acids, nitric oxide (NO)/reactive oxygen species balance, and endothelin-1 in conduit artery endothelial dysfunction during essential hypertension.
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