Cardioprotection Through S -Nitros(yl)ation of Macrophage Migration Inhibitory Factor | Zendy

Peter Luedike | Zendy; Ulrike B. HendgenCotta | Zendy; Julia Sobierajski | Zendy; Matthias Totzeck | Zendy; Marcel Reeh | Zendy; Manfred Dewor | Zendy; Hongqi Lue | Zendy; Christoph Krisp | Zendy; Dirk Wolters | Zendy; Malte Kelm | Zendy; Jürgen Bernhagen | Zendy; Tienush Rassaf | Zendy

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Cardioprotection Through S -Nitros(yl)ation of Macrophage Migration Inhibitory Factor

Author(s) -

Peter Luedike,

Ulrike B. HendgenCotta,

Julia Sobierajski,

Matthias Totzeck,

Marcel Reeh,

Manfred Dewor,

Hongqi Lue,

Christoph Krisp,

Dirk Wolters,

Malte Kelm,

Jürgen Bernhagen,

Tienush Rassaf

Publication year - 2012

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.111.069104

Subject(s) - macrophage migration inhibitory factor , cytoprotection , cardioprotection , medicine , in vivo , macrophage , pharmacology , cytokine , inflammation , microbiology and biotechnology , immunology , oxidative stress , biology , in vitro , biochemistry , ischemia

Macrophage migration inhibitory factor (MIF) is a structurally unique inflammatory cytokine that controls cellular signaling in human physiology and disease through extra- and intracellular processes. Macrophage migration inhibitory factor has been shown to mediate both disease-exacerbating and beneficial effects, but the underlying mechanism(s) controlling these diverse functions are poorly understood.

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