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Letter by Nezami et al Regarding Article, “Platelet Reactivity and Cardiovascular Outcomes After Percutaneous Coronary Intervention: A Time-Dependent Analysis of the Gauging Responsiveness With a VerifyNow P2Y12 Assay: Impact on Thrombosis and Safety (GRAVITAS) Trial”
Author(s) -
Nariman Nezami,
Ourmaan Nezami Nargabad,
Sona Ghorashi
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.068346
Subject(s) - medicine , percutaneous coronary intervention , clopidogrel , p2y12 , conventional pci , acute coronary syndrome , cardiology , coronary artery disease , aspirin , myocardial infarction
To the Editor:We read with great interest the article by Price et al1 in a recent issue of Circulation . The authors concluded that achievement of on-treatment platelet reactivity (OTR) <208 P2Y12 reaction units at 12 to 24 hours after percutaneous coronary intervention (PCI) or during follow-up was associated with a lower risk for cardiovascular events. Considering the potential clinical implications of this attractive study, addressing some methodological issues would be appreciated.The GRAVITAS trial1 enrolled patients after PCI with 1 or more drug-eluting stents for the treatment of stable coronary artery disease or non–ST-elevation acute …

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