Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans
Author(s) -
Susan Cheng,
Eugene P. Rhee,
Martin G. Larson,
Gregory D. Lewis,
Elizabeth L. McCabe,
Dongxiao Shen,
Melinda J. Palma,
Lee D. Roberts,
Andrè Dejam,
Amanda L. Souza,
Amy Deik,
Martin Magnusson,
Caroline S. Fox,
Christopher J. O’Donnell,
Ramachandran S. Vasan,
Olle Melander,
Clary B. Clish,
Robert E. Gerszten,
Thomas J. Wang
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.067827
Subject(s) - glutamine , medicine , insulin resistance , endocrinology , diabetes mellitus , dyslipidemia , metabolite , metabolic syndrome , blood pressure , odds ratio , framingham heart study , metabolic pathway , type 2 diabetes , framingham risk score , amino acid , disease , biochemistry , metabolism , biology
Although metabolic risk factors are known to cluster in individuals who are prone to developing diabetes mellitus and cardiovascular disease, the underlying biological mechanisms remain poorly understood.
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