Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation
Author(s) -
Maria Salagianni,
Ioanna E. Galani,
Anna M. Lundberg,
Constantinos H. Davos,
Aimilia Varela,
Ariana Gavriil,
LeoPekka Lyytikäinen,
Terho Lehtimäki,
Fragiska Sigala,
Lasse Folkersen,
Vassilis G. Gorgoulis,
Sébastien Lenglet,
Fabrizio Montecucco,
François Mach,
Ulf Hedin,
Göran K. Hansson,
Claudia Monaco,
Evangelos Andreakos
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.067678
Subject(s) - medicine , macrophage , inflammation , toll like receptor , receptor , immunology , innate immune system , microbiology and biotechnology , biochemistry , in vitro , biology , chemistry
Toll-like receptors (TLRs) have long been considered to be major culprits in the development of atherosclerosis, contributing both to its progression and clinical complications. However, evidence for most TLRs beyond TLR2 and TLR4 is lacking.
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