Open AccessLong-Term Effects of Sildenafil in a Rat Model of Chronic Mitral Regurgitation
Author(s) -
KyungHee Kim,
YongJin Kim,
Jung-Hun Ohn,
Jimin Yang,
SangEun Lee,
Sae-Won Lee,
HyungKwan Kim,
JeongWook Seo,
DaeWon Sohn
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.065300
Subject(s) - medicine , sildenafil , cardiology , mitral regurgitation , term (time) , functional mitral regurgitation , regurgitation (circulation) , heart failure , ejection fraction , physics , quantum mechanics
We tested the hypothesis that chronic treatment with sildenafil attenuates left ventricular (LV) remodeling and prevents exercise intolerance in chronic mitral regurgitation (MR).
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