Open AccessWhite Matter Protection in Congenital Heart Surgery
Author(s) -
Nobuyuki Ishibashi,
Joseph Scafidi,
Akira Murata,
Ludmila Korotcova,
David Zurakowski,
Vittorio Gallo,
Richard A. Jonas
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.048215
Subject(s) - medicine , cardiology , surgery
Neurodevelopmental delays in motor skills and white matter (WM) injury have been documented in congenital heart disease and after pediatric cardiac surgery. The lack of a suitable animal model has hampered our understanding of the cellular mechanisms underlying WM injury in these patients. Our aim is to identify an optimal surgical strategy for WM protection to reduce neurological injury in congenital heart disease patients.
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