Conduction Remodeling in Human End-Stage Nonischemic Left Ventricular Cardiomyopathy | Zendy

Alexey V. Glukhov | Zendy; Vadim V. Fedorov | Zendy; Paul W. Kalish | Zendy; Vinod K. Ravikumar | Zendy; Qing Lou | Zendy; Deborah Janks | Zendy; Richard B. Schuessler | Zendy; Nader Moazami | Zendy; Igor R. Efimov | Zendy

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Conduction Remodeling in Human End-Stage Nonischemic Left Ventricular Cardiomyopathy

Author(s) -

Alexey V. Glukhov,

Vadim V. Fedorov,

Paul W. Kalish,

Vinod K. Ravikumar,

Qing Lou,

Deborah Janks,

Richard B. Schuessler,

Nader Moazami,

Igor R. Efimov

Publication year - 2012

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.111.047274

Subject(s) - medicine , cardiology , endocardium , heart failure , repolarization , cardiomyopathy , connexin , downregulation and upregulation , nerve conduction velocity , optical mapping , gap junction , cardiac resynchronization therapy , electrical conduction system of the heart , ischemic cardiomyopathy , ventricular remodeling , electrophysiology , electrocardiography , intracellular , ejection fraction , chemistry , biochemistry , gene

Several arrhythmogenic mechanisms have been inferred from animal heart failure models. However, the translation of these hypotheses is difficult because of the lack of functional human data. We aimed to investigate the electrophysiological substrate for arrhythmia in human end-stage nonischemic cardiomyopathy.

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