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Letter by Falk Regarding Article, “An Unusual Heart Failure: Cardiac Amyloidosis Due to Light Chain Myeloma”
Author(s) -
Rodney H. Falk
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.046953
Subject(s) - multiple myeloma , medicine , plasma cell dyscrasia , amyloidosis , cardiac amyloidosis , immunoglobulin light chain , dyscrasia , al amyloidosis , heart failure , pathology , bone marrow , restrictive cardiomyopathy , plasma cell , cardiomyopathy , antibody , immunology
To the Editor:I found the case report by Martinelli et al, “An Unusual Heart Failure: Cardiac Amyloidosis due to Light Chain Myeloma,”1 interesting, but, unfortunately, I believe that the authors have perpetuated a common misperception in describing the patient as having smoldering myeloma. Careful examination of the data presented indicates that their patient did not have multiple myeloma, and I believe that their conclusion that “light chain myeloma—may be a cause of cardiac amyloidosis” is semantically incorrect.Light chain (AL) amyloidosis is a …

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