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Heparin Elevates Circulating Soluble fms-Like Tyrosine Kinase-1 Immunoreactivity in Pregnant Women Receiving Anticoagulation Therapy
Author(s) -
Victor Rosenberg,
Irina A. Buhimschi,
Charles J. Lockwood,
Michael J. Paidas,
Antonette T. Dulay,
Wenda Ramma,
Sonya S. AbdelRazeq,
Guomao Zhao,
Shakil Ahmad,
Asif Ahmed,
Catalin S. Buhimschi
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.046821
Subject(s) - medicine , soluble fms like tyrosine kinase 1 , placental growth factor , heparin , preeclampsia , endocrinology , angiogenesis , placenta , tyrosine kinase , vascular endothelial growth factor , fetus , andrology , pregnancy , receptor , biology , genetics , vegf receptors
Alterations in circulating levels of pro- and antiangiogenic factors have been associated with adverse pregnancy outcomes. Heparin is routinely administered to pregnant women, but without clear knowledge of its impact on these factors.

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