C/EBP Homologous Protein-10 (CHOP-10) Limits Postnatal Neovascularization Through Control of Endothelial Nitric Oxide Synthase Gene Expression
Author(s) -
Céline Loinard,
Yasmine Zouggari,
Patricia Rueda,
Bhama Ramkhelawon,
Clément Cochain,
José Vilar,
Alice Récalde,
Adèle Richart,
Dominique Charue,
Micheline Duriez,
Masataka Mori,
Fernando ArenzanaSeisdedos,
Bernard Lévy,
Christophe Heymes,
JeanSébastien Silvestre
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.041830
Subject(s) - chop , enos , medicine , downregulation and upregulation , endocrinology , nitric oxide synthase , nitric oxide synthase type iii , neovascularization , nitric oxide , biology , angiogenesis , biochemistry , gene , lymphoma
C/EBP homologous protein-10 (CHOP-10) is a novel developmentally regulated nuclear protein that emerges as a critical transcriptional integrator among pathways regulating differentiation, proliferation, and survival. In the present study, we analyzed the role of CHOP-10 in postnatal neovascularization.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom