Sirolimus as Primary Immunosuppression Attenuates Allograft Vasculopathy With Improved Late Survival and Decreased Cardiac Events After Cardiac Transplantation
Author(s) -
Yan Topilsky,
Tal Hasin,
Eugenia Raichlin,
Barry A. Boilson,
John A. Schirger,
Naveen L. Pereira,
Brooks S. Edwards,
Alfredo L. Clavell,
Richard J. Rodeheffer,
Robert P. Frantz,
Simon Maltais,
Soon J. Park,
Richard C. Daly,
Amir Lerman,
Sudhir S. Kushwaha
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.040360
Subject(s) - medicine , calcineurin , sirolimus , transplantation , intravascular ultrasound , heart transplantation , immunosuppression , ejection fraction , cardiology , urology , surgery , heart failure
We retrospectively analyzed the potential of sirolimus as a primary immunosuppressant in the long-term attenuation of cardiac allograft vasculopathy progression and the effects on cardiac-related morbidity and mortality.
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