Cardiac Biomarkers Are Associated With an Increased Risk of Stroke and Death in Patients With Atrial Fibrillation
Author(s) -
Ziad Hijazi,
Jonas Oldgren,
Ulrika Andersson,
Stuart J. Connolly,
Michael D. Ezekowitz,
Stefan H. Hohnloser,
Paul Reilly,
Dragoş Vinereanu,
Agneta Siegbahn,
Salim Yusuf,
Lars Wallentin
Publication year - 2012
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.111.038729
Subject(s) - medicine , atrial fibrillation , hazard ratio , quartile , natriuretic peptide , cardiology , stroke (engine) , troponin , biomarker , troponin i , randomization , proportional hazards model , randomized controlled trial , myocardial infarction , heart failure , confidence interval , mechanical engineering , engineering , biochemistry , chemistry
Cardiac biomarkers are strong predictors of adverse outcomes in several patient populations. We evaluated the prevalence of elevated troponin I and N-terminal pro-B-type natriuretic peptide (NT-proBNP) and their association to cardiovascular events in atrial fibrillation (AF) patients in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial.
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