Role of Perivascular Adipose Tissue–Derived Methyl Palmitate in Vascular Tone Regulation and Pathogenesis of Hypertension | Zendy

YuanChieh Lee | Zendy; HsiHsien Chang | Zendy; ChihLung Chiang | Zendy; ChinHung Liu | Zendy; JihI Yeh | Zendy; MeiFang Chen | Zendy; PoYi Chen | Zendy; JonSon Kuo | Zendy; Tony J.-F. Lee | Zendy

Open Access

Role of Perivascular Adipose Tissue–Derived Methyl Palmitate in Vascular Tone Regulation and Pathogenesis of Hypertension

Author(s) -

YuanChieh Lee,

HsiHsien Chang,

ChihLung Chiang,

ChinHung Liu,

JihI Yeh,

MeiFang Chen,

PoYi Chen,

JonSon Kuo,

Tony J.-F. Lee

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.111.027375

Subject(s) - medicine , endocrinology , apamin , losartan , angiotensin ii , adipose tissue , vascular smooth muscle , iberiotoxin , pharmacology , chemistry , vasodilation , calcium , blood pressure , smooth muscle

Perivascular adipose tissue (PVAT)-derived relaxing factor (PVATRF) significantly regulates vascular tone. Its chemical nature remains unknown. We determined whether palmitic acid methyl ester (PAME) was the PVATRF and whether its release and/or vasorelaxing activity decreased in hypertension.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research