Coronary Artery Wall Shear Stress Is Associated With Progression and Transformation of Atherosclerotic Plaque and Arterial Remodeling in Patients With Coronary Artery Disease | Zendy

Habib Samady | Zendy; Parham Eshtehardi | Zendy; Michael McDaniel | Zendy; Jin Suo | Zendy; Saurabh S. Dhawan | Zendy; Charles Maynard | Zendy; Lucas H. Timmins | Zendy; Arshed A. Quyyumi | Zendy; Don P. Giddens | Zendy

Open Access

Coronary Artery Wall Shear Stress Is Associated With Progression and Transformation of Atherosclerotic Plaque and Arterial Remodeling in Patients With Coronary Artery Disease

Author(s) -

Habib Samady,

Parham Eshtehardi,

Michael McDaniel,

Jin Suo,

Saurabh S. Dhawan,

Charles Maynard,

Lucas H. Timmins,

Arshed A. Quyyumi,

Don P. Giddens

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.111.021824

Subject(s) - medicine , cardiology , coronary artery disease , artery , shear stress , arterial wall , composite material , materials science

Experimental studies suggest that low wall shear stress (WSS) promotes plaque development and high WSS is associated with plaque destabilization. We hypothesized that low-WSS segments in patients with coronary artery disease develop plaque progression and high-WSS segments develop necrotic core progression with fibrous tissue regression.

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