Intracardiac Electrogram T-Wave Alternans/Variability Increases Before Spontaneous Ventricular Tachyarrhythmias in Implantable Cardioverter-Defibrillator Patients | Zendy

Charles D. Swerdlow | Zendy; Theodore Chow | Zendy; Mithilesh K. Das | Zendy; Anne M. Gillis | Zendy; Xiaohong Zhou | Zendy; Athula Abeyratne | Zendy; Raja N. Ghanem | Zendy

Open Access

Intracardiac Electrogram T-Wave Alternans/Variability Increases Before Spontaneous Ventricular Tachyarrhythmias in Implantable Cardioverter-Defibrillator Patients

Author(s) -

Charles D. Swerdlow,

Theodore Chow,

Mithilesh K. Das,

Anne M. Gillis,

Xiaohong Zhou,

Athula Abeyratne,

Raja N. Ghanem

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.986364

Subject(s) - medicine , cardiology , implantable cardioverter defibrillator , ventricular tachycardia , ventricular fibrillation , supraventricular tachycardia , t wave alternans , ambulatory , defibrillation , tachycardia , sudden cardiac death

T-wave alternans (TWA) increases before ventricular tachycardia (VT) or fibrillation (VF), suggesting that it may warn of VT/VF in implantable cardioverter-defibrillator patients. Recently, we described a method for measuring alternans and nonalternans variability (TWA/V) from electrograms (EGMs) stored in implantable cardioverter-defibrillators before VT/VF. The goal of this prospective, multicenter study was to determine whether EGM TWA/V was greater before VT/VF than at baseline.

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