Open AccessImpact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation
Author(s) -
David Goldberg,
Benjamin French,
Michael G. McBride,
Bradley S. Marino,
Nicole Mirarchi,
Brian D. Hanna,
Gil Wernovsky,
Stephen M. Paridon,
Jack Rychik
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.110.981746
Subject(s) - medicine , sildenafil , cardiology , fontan procedure , physical therapy , heart disease
Children and young adults with single-ventricle physiology have abnormal exercise capacity after the Fontan operation. A medication capable of decreasing pulmonary vascular resistance should allow improved cardiac filling and improved exercise capacity.
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