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Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction
Author(s) -
Christopher J. O’Donnell,
Maryam Kavousi,
Albert V. Smith,
Sharon L. R. Kardia,
Mary F. Feitosa,
Shih-Jen Hwang,
Yan V. Sun,
Michael A. Province,
Thor Aspelund,
Abbas Dehghan,
Udo Hoffmann,
Lawrence F. Bielak,
Qunyuan Zhang,
Guðný Eiríksdóttir,
Cornelia M. van Duijn,
Caroline S. Fox,
Mariza de Andrade,
Aldi T. Kraja,
Sigurður Sigurðsson,
Suzette E. EliasSmale,
Joanne M. Murabito,
Lenore J. Launer,
Aad van der Lugt,
Sekar Kathiresan,
Gabriël P. Krestin,
David M. Herrington,
Timothy D. Howard,
Yongmei Liu,
Wendy S. Post,
Braxton D. Mitchell,
Jeffrey R. O’Connell,
Haiqing Shen,
Alan R. Shuldiner,
David Altshuler,
Roberto Elosúa,
Veikko Salomaa,
Stephen M. Schwartz,
David S. Siscovick,
Benjamin F. Voight,
Joshua C. Bis,
Nicole L. Glazer,
Bruce M. Psaty,
Eric Boerwinkle,
Gerardo Heiss,
Stefan Blankenberg,
Tanja Zeller,
Philipp S. Wild,
Renate B. Schnabel,
Arne Schillert,
Andreas Ziegler,
Thomas F. Münzel,
Charles C. White,
Jerome I. Rotter,
Michael A. Nalls,
Matthijs Oudkerk,
Andrew D. Johnson,
Anne B. Newman,
André G. Uitterlinden,
Joseph M. Massaro,
Julie M. Cunningham,
Tamara B. Harris,
Albert Hofman,
Patricia A. Peyser,
Ingrid B. Borecki,
L. Adrienne Cupples,
Vilmundur Guðnason,
Jacqueline C.M. Witteman
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.110.974899
Subject(s) - genome wide association study , single nucleotide polymorphism , medicine , snp , genetic association , myocardial infarction , genetics , coronary artery disease , cardiology , gene , biology , genotype
Coronary artery calcification (CAC) detected by computed tomography is a noninvasive measure of coronary atherosclerosis, which underlies most cases of myocardial infarction (MI). We sought to identify common genetic variants associated with CAC and further investigate their associations with MI.

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