Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity | Zendy

Olga Gealekman | Zendy; N. I. Guseva | Zendy; Celia Hartigan | Zendy; Sarah Apotheker | Zendy; Matthew Gorgoglione | Zendy; Kunal Gurav | Zendy; KhanhVan Tran | Zendy; Juerg Straubhaar | Zendy; Sarah M. Nicoloro | Zendy; Michael Czech | Zendy; Michael Thompson | Zendy; Richard A. Perugini | Zendy; Silvia Corvera | Zendy

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Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity

Author(s) -

Olga Gealekman,

N. I. Guseva,

Celia Hartigan,

Sarah Apotheker,

Matthew Gorgoglione,

Kunal Gurav,

KhanhVan Tran,

Juerg Straubhaar,

Sarah M. Nicoloro,

Michael Czech,

Michael Thompson,

Richard A. Perugini,

Silvia Corvera

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.970145

Subject(s) - medicine , adipose tissue , angiogenesis , subcutaneous fat , obesity , subcutaneous adipose tissue , human obesity , depot , subcutaneous tissue , endocrinology , pathology , archaeology , history

Adipose tissue expands in response to excess caloric intake, but individuals prone to deposit visceral instead of subcutaneous adipose tissue have higher risk of metabolic disease. The role of angiogenesis in the expandability of human adipose tissue depots is unknown. The objective of this study was to measure angiogenesis in visceral and subcutaneous adipose tissue and to establish whether there is a relationship between obesity, metabolic status, and the angiogenic properties of these depots.

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