MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation | Zendy

Yanjie Lu | Zendy; Ying Zhang | Zendy; Ning Wang | Zendy; Zhenwei Pan | Zendy; Xu Gao | Zendy; Fengmin Zhang | Zendy; Yong Zhang | Zendy; Hongli Shan | Zendy; Xiaobin Luo | Zendy; Yunlong Bai | Zendy; Lihua Sun | Zendy; Wuqi Song | Zendy; Chaoqian Xu | Zendy; Zhiguo Wang | Zendy; Baofeng Yang | Zendy

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MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation

Author(s) -

Yanjie Lu,

Ying Zhang,

Ning Wang,

Zhenwei Pan,

Xu Gao,

Fengmin Zhang,

Yong Zhang,

Hongli Shan,

Xiaobin Luo,

Yunlong Bai,

Lihua Sun,

Wuqi Song,

Chaoqian Xu,

Zhiguo Wang,

Baofeng Yang

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.958967

Subject(s) - atrial fibrillation , medicine , microrna , gene knockdown , cardiology , transcriptome , antagomir , atrial action potential , gene expression , gene , electrophysiology , biology , repolarization , genetics

A characteristic of both clinical and experimental atrial fibrillation (AF) is atrial electric remodeling associated with profound reduction of L-type Ca(2+) current and shortening of the action potential duration. The possibility that microRNAs (miRNAs) may be involved in this process has not been tested. Accordingly, we assessed the potential role of miRNAs in regulating experimental AF.

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