Acetaminophen Increases Blood Pressure in Patients With Coronary Artery Disease
Author(s) -
Isabella Sudano,
Andreas J. Flammer,
Daniel Périat,
Frank Enseleit,
Matthias Hermann,
Mathias Wolfrum,
A. Hirt,
P. Kaiser,
David Hürlimann,
Michel Neidhart,
Steffen Gay,
Johannes Holzmeister,
Juerg Nussberger,
Pavani Mocharla,
Ulf Landmesser,
Sarah R. Haile,
Roberto Corti,
Paul M. Vanhoutte,
Thomas F. Lüscher,
Georg Noll,
Frank Ruschitzka
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.110.956490
Subject(s) - medicine , coronary artery disease , blood pressure , cardiology , disease
Because traditional nonsteroidal antiinflammatory drugs are associated with increased risk for acute cardiovascular events, current guidelines recommend acetaminophen as the first-line analgesic of choice on the assumption of its greater cardiovascular safety. Data from randomized clinical trials prospectively addressing cardiovascular safety of acetaminophen, however, are still lacking, particularly in patients at increased cardiovascular risk. Hence, the aim of this study was to evaluate the safety of acetaminophen in patients with coronary artery disease.
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