Effect of Cardiac Resynchronization Therapy on Reverse Remodeling and Relation to Outcome | Zendy

Scott D. Solomon | Zendy; Elyse Foster | Zendy; Mikhail Bourgoun | Zendy; Amil M. Shah | Zendy; Esperanza Viloria | Zendy; Mary W. Brown | Zendy; William J. Hall | Zendy; Marc A. Pfeffer | Zendy; Arthur J. Moss | Zendy

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Effect of Cardiac Resynchronization Therapy on Reverse Remodeling and Relation to Outcome

Author(s) -

Scott D. Solomon,

Elyse Foster,

Mikhail Bourgoun,

Amil M. Shah,

Esperanza Viloria,

Mary W. Brown,

William J. Hall,

Marc A. Pfeffer,

Arthur J. Moss

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.955039

Subject(s) - medicine , cardiac resynchronization therapy , cardiology , ventricular remodeling , heart failure , outcome (game theory) , ejection fraction , mathematics , mathematical economics

Cardiac resynchronization therapy (CRT) plus implantation of an implantable cardioverter defibrillator (ICD) reduced the risk of death or heart failure event in patients with mildly symptomatic heart failure, left ventricular dysfunction, and wide QRS complex compared with an ICD only. We assessed echocardiographic changes in patients enrolled in the MADIT-CRT trial (Multicenter Automatic Defibrillator Implantation Trial: Cardiac Resynchronization Therapy) to evaluate whether the improvement in outcomes with CRT plus an ICD was associated with favorable alterations in cardiac size and function.

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