Glucose-Insulin-Potassium Reduces the Incidence of Low Cardiac Output Episodes After Aortic Valve Replacement for Aortic Stenosis in Patients With Left Ventricular Hypertrophy | Zendy

Neil Howell | Zendy; Houman Ashrafian | Zendy; Nigel E Drury | Zendy; Aaron Ranasinghe | Zendy; Hussain Contractor | Zendy; Henrik Isackson | Zendy; Melanie Calvert | Zendy; Lynne Williams | Zendy; Nick Freemantle | Zendy; David W. Quinn | Zendy; David Green | Zendy; Michael Frenneaux | Zendy; Robert S. Bonser | Zendy; Jorge Mascaro | Zendy; Timothy R. Graham | Zendy; Stephen J. Rooney | Zendy; Ian C. Wilson | Zendy; Duilio Pagano | Zendy

Open Access

Glucose-Insulin-Potassium Reduces the Incidence of Low Cardiac Output Episodes After Aortic Valve Replacement for Aortic Stenosis in Patients With Left Ventricular Hypertrophy

Author(s) -

Neil Howell,

Houman Ashrafian,

Nigel E Drury,

Aaron Ranasinghe,

Hussain Contractor,

Henrik Isackson,

Melanie Calvert,

Lynne Williams,

Nick Freemantle,

David W. Quinn,

David Green,

Michael Frenneaux,

Robert S. Bonser,

Jorge Mascaro,

Timothy R. Graham,

Stephen J. Rooney,

Ian C. Wilson,

Duilio Pagano

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.945170

Subject(s) - medicine , aortic valve replacement , cardiology , left ventricular hypertrophy , aortic valve , aortic valve stenosis , odds ratio , stenosis , blood pressure

Patients undergoing aortic valve replacement for critical aortic stenosis often have significant left ventricular hypertrophy. Left ventricular hypertrophy has been identified as an independent predictor of poor outcome after aortic valve replacement as a result of a combination of maladaptive myocardial changes and inadequate myocardial protection at the time of surgery. Glucose-insulin-potassium (GIK) is a potentially useful adjunct to myocardial protection. This study was designed to evaluate the effects of GIK infusion in patients undergoing aortic valve replacement surgery.

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