Urokinase-Type Plasminogen Activator Promotes Paracellular Transmigration of Neutrophils Via Mac-1, But Independently of Urokinase-Type Plasminogen Activator Receptor
Author(s) -
Christoph A. Reichel,
Bernd Uhl,
Max Lerchenberger,
Daniel PuhrWesterheide,
Markus Rehberg,
Johanna Liebl,
Andrej Khandoga,
Wolfgang A. Schmalix,
Stefan Zahler,
Elisabeth Deindl,
Stefan Lorenzl,
Paul Declerck,
Sandip M. Kanse,
Fritz Krombach
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.110.017012
Subject(s) - urokinase receptor , plasminogen activator , medicine , urokinase , receptor , in vivo , integrin alpha m , immunology , microbiology and biotechnology , endocrinology , biology
Urokinase-type plasminogen activator (uPA) has recently been implicated in the pathogenesis of ischemia-reperfusion (I/R) injury. The underlying mechanisms remain largely unclear.
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